The "Active" Ingredient in Many Popular Hair Loss Treatment Products

Many popular hair loss treatment options today such as Provillus, Procerin, and Avacor contain the “active” ingredient saw palmetto. It can also be purchased as a standalone supplement in most nutritional stores. But the age old question of whether or not it can effectively treat baldness in men and women with alopecia is still heavily debated. By taking a look at the scientific evidence available we are able to draw some conclusions as to its potential benefit for those with thinning hair.

What is Saw Palmetto?

Saw Palmetto berries are a deep red fruit that grow wild on palm trees in warmer climates, typically found in the Southeastern United States. The liposerolic berry extract is typically used as an herbal supplement for the promotion of a healthy prostate.

Saw Palmetto Hair Loss Study:

Similarly to finasteride (the active ingredient in Propecia and Proscar), studies have shown that when taken orally, it may be an effective anti-androgen by lowering dihydrotestosterone (DHT) levels in the body by blocking 5 alpha-reductase enzymes. Additionally it is said to block receptor cites on cells which is required for cells to absorb DHT.

Tests have also been performed on its use in the treatment of benign prostatic disease, which similarly to androgenic alopecia, depends on the production of DHT.

It is also noteworthy to state that a small preliminary study in 2002 was performed as reported by The Journal of Alternative and Complementary Medicine(2002;8:143-52) that shows a select group of 19 men between the ages of 23 and 64 taking either (400mg of saw palmetto and 100mg of Beta-sitosterol) or a placebo orally. Those who took the herbal combination had 60% improved hair growth over those who took the placebo. There have been no studies to date indicating the efficacy of saw palmetto applied topically for male pattern baldness, female hair loss, or anything to date.

In our opinion, there are two potential difficulties with this study:

• Many scientists would argue that the control study group was too small to determine any real efficacy and improved hair growth could have happened by chance. A larger study therefore may be necessary to determine any level of real efficacy.
• “Improved hair growth” is not the same thing as newhair growth and hair regrowth, nor should it necessarily imply that it works to stop hair loss
• There are no regulations or suggested daily value as to how much saw palmetto would be required to successfully treat baldness. The appropriate dosage therefore is questionable.
• The above study was only performed on saw palmetto taken orally. Hair loss products that promote topical use for baldness are basing their belief in its efficacy on something other than published clinical evidence.

The Dosage:

But if there are no current standards on dosages of herbal medications in the United States, how do these popular hair loss treatments produce an appropriate dosage?

Clinical studies on Benign Prostrate Hyperplasia (BPH) have used a dosage of 320mg of the berry extract daily (either one 320mg pill or 2 X 160 mg pill). A daily dosage of 480 mg of saw palmetto berry extract was not found to be any more effective in a six-month study. If the entire berry was used, up to 1000mg or 2000mg would be required to reach the same goal.

The theory therefore is that if saw palmetto can successfully treat an enlarged prostate similarly to finasteride, it can effectively treat hair loss with a similar dosage Many popular “baldness cure” products contain approximately 1500mg of the berry which is equivalent to approximately 240-320mg of the berry extract.

Side Effects and Warnings:

One false assumption is that “all natural” treatments don’t have potential side effects. It is stated that use of saw palmetto has not proven to be safe for women with hair loss during pregnancy and lactation. Medical supervision is suggested for women of childbearing age. Similar warnings are listed about Propecia.

Conclusions:

Based on some anecdotal evidence, saw palmetto is said to treat baldness because of its tendency to act like finasteride by helping those suffering from BPH. However, authentic clinical studies have not been performed to date that support this claim. Dosage and how it should be used (orally or topically) therefore is based on conjecture rather that scientific evidence.

For many hair loss suffering men and women, topical concealers are a necessary aspect of the "daily routine." Usually composed of hair shaft adhering microfibers or darkening cream, concealers help balding men and women both camouflage areas of noticeable baldness and increase the apparent density of thinning hair. Below, we provide our readers with a product review of the new and popular hair loss concealer Caboki.

Caboki was released back in 2005 but is only just now receiving more attention, most likely due to increased advertising. Like others before it, Caboki concealer claims to be a "hair loss breakthrough". Despite ambitious promises, Caboki's claims leave several unanswered questions: is Caboki really a breakthrough concealer? How does it compare to other, similar products like Toppik, DermMatch and COUVre? Is Caboki a worthwhile product for purchasing, or will it fall from grace like other alleged "breakthrough" hair loss miracles before it?

While many products, such as "Toppik" (a popular microfiber-style concealer) and "Couvre" (a concealing cream) are popular and trusted within the hair loss community, new, unproven concealers arrive on the market every day. What's more, many of these new concealers try to "best" the products currently offered and claim to camouflage hair loss in a way "never seen before." However, as with many alleged miracle cures, these products often fail to meet expectations and leave hair loss sufferers disappointed and discouraged. So let's explore how Caboki works to conceal hair loss below.

Caboki is comprised of a series of charged microfibers that, when applied to the scalp, tightly bind hair shafts and create a denser, fuller appearance. According to the manufacturer, these microfibers are comprised of two different elements: Moroccan Gossypium Herbaceum fiber and iron oxide-based natural (mineral-based) colorants. The makers of Caboki claim these elements allow the product to create a natural, healthy appearance, capable of withstanding harsh lighting conditions, sweat, wind, and rain.

However, because these elements have been used in other concealer products (Toppik particles, for example, are both charged and made from natural keratin), Caboki still must demonstrate why it's revolutionary. So, what makes Caboki a "hair loss breakthrough?" According to the manufactures, Caboki differs from other concealers in the following ways:

• Caboki particles, unlike other microfiber concealers, are negatively, not positively charged. Allegedly, positively charged particles (usually made from wool fibers) possess a greater tendency to repel and oppose not only each other, but also the positively charged hair shafts. Because of this, when the particles attach near each other on a hair shaft, they are more likely to repel and detach. According to Caboki creators, negatively charged fibers (made from Moroccan Gossypium Herbaceum fiber) do not experience this intense phenomenon, and create a much greater (200%), electronically attractive (negative to positive), bond. If this is true, Caboki microfibers should bind and adhere to hair shafts with a much stronger, more permanent affinity.
• Because Caboki particles create a stronger charged bond, the thicker, more volumized hair shafts are likely to stand erect and less non-bonded concealer will collect on the scalp. This combination, according to Caboki, will eliminate the "dull, flat" appearance associated with other concealer products.
• By only utilizing natural elements (Moroccan Gossypium Herbaceum fibers and iron oxide colorants), Caboki avoids some of the potentially harmful synthetic dyes, fillers, and artificial preservatives used in other concealer products.

So, it's now clear why the manufacturers of Caboki believe it is a superior product, but does this mean Caboki is a legitimate hair loss concealer? Does it truly outshine other concealer product currently on the market?

While the product is still fairly new, most anecdotal experiences and testimonials from real hair loss suffering men and women are positive. Most individuals believe the negatively charged Caboki particles bind strongly to the positively charged hair shafts and create a longer-lasting increase in density. Furthermore, the particles seem to be more resistant to potentially damaging elements like water, sweat, and wind. Having said that, many individuals report some common problems experienced with other concealer products – concealer wiping off on pillows and clothes, some smearing with sweat, and difficultly creating a natural appearance in the hairline. However, these same individuals claim the problems occur less frequently with Caboki. Altogether, it's likely that Caboki is both a helpful hair loss concealer and equivalent to other products currently on the market. While it is clear that Caboki does possess some advantages and interesting claims, it could be difficult to quantify whether it truly exceeds or simply meets the standard set by other available hair loss concealers. Truthfully, only time and the opinion of hair loss sufferers will determine whether Caboki lives up to its claims and defines itself as a legitimate concealer breakthrough.

As patients, we know that the physician you choose is the most critical decision in restoring your hair is the physician you choose. Hair restoration physicians' skills, experience, and talent vary widely, as do the end results, vary widely.

You must research and choose your physician wisely. After all, who you choose will determine how natural and complete, your new hair will be for the rest of your life. The surgeons selected and approved by our community have been scouted and vetted by the forum's highly esteemed senior valued contributors of the Hair Restoration Network. Our valued contributors have all spent years researching hair transplantation, and they have all had hair transplants. To ensure there is no conflict of interest, none of our valued contributors receive any compensation. They are volunteers who have shared their experiences and contributed for years to our community. Each surgeon has been approved based on their ethics, surgical techniques, results, and reviews. To support the costs of operating and promoting our community, the approved physician contributes a monthly fee to sponsor our community.

Their recommendation is continued as long as they continue to show evidence of excellent patient results and satisfaction. If a patient expresses concerns, physicians are expected to resolve their concerns. We ask that patients first contact a physician with any concerns so that they can resolve them before publicly posting.

Note - The hair restoration physicians recommended on this site are not a definitive list of all excellent hair transplant doctors. Nor do we warrant or guarantee the results of any of the physicians presented on this site. As always, we encourage you to do your due diligence in evaluating these and all hair loss physicians.

We offer the following suggestions for researching a hair restoration physician:

• Does the physician take a holistic approach to hair restoration? Your physician should help you evaluate all your options, surgical and non-surgical.
• Have they invested time and resources in large micro follicular unit hair transplantation sessions? Outstanding work requires a staff dedicated to and trained to use high-powered magnification to produce more than 2,000 carefully trimmed grafts per surgical session.
• Choose a hair restoration clinic that is patient-focused rather than commercially focused. Some clinics emphasize revenue, speed, and volume rather than dedicating the time and individual care needed to produce optimal results. These commercial operations typically rely on heavy advertising rather than satisfied patient or doctor referrals.
• Is hair restoration the primary focus of their practice? Outstanding results require a physician and staff to perform hair restoration surgery regularly. Doing hair restoration as a sideline and other cosmetic procedures may hinder their ability to do large sessions of highly refined follicular unit transplantation.
• How many patients has this physician produced excellent results for? Like any skill, experience over time is critical to acquiring the skill and judgment required to produce excellent results.
• Can the physician provide detailed patient before and after photographs? Do they also have patients who are willing to speak with you and meet with you in person?

What do their hair transplant patients think?

Ultimately, the most critical measure of a hair transplant surgeon's work is their patient's level of satisfaction. Find out what patients think of their physician's work by visiting our discussion forum or viewing hair loss blogs created by patients. View our standards for recommending hair transplant surgeons.

Find an excellent hair restoration physician in your area.

Send a Virtual Consult

This online feature enables you to fill out a hair loss questionnaire and email it to any of the quality hair loss doctors recommended on this site. You can even attach your photos. They will then respond to your questions and concerns.

Click here, to send a Virtual Consult.

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We are always interested in learning about outstanding hair restoration physicians. Click below to suggest an outstanding physician for recommendation on this site.
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One of the more popular hair loss products on the market today for those with thinning hair is Provillus. Available for both men and women, making promises to “re-grow beautiful healthy hair”, this product consists of a topical and oral solution with an FDA approved hair regrowth ingredient and a number of conjectured “all-natural” dihydrotestosterone (DHT) blockers.

Other ingredients that promote a healthy scalp and head of hair are also contained in this product. The theory behind Provillus is to revive the hair follicles with growth stimulators and attack hair loss at its source by blocking DHT.

In order to fully evaluate the efficacy of this product, we must further explore each ingredient to determine whether or not this hair loss treatment delivers what it promises. Below you will find a list of ingredients and information that will help you determine whether or not Provillus is right for you.

Topical Ingredients:

Minoxidil (found in Rogaine, Xandrox and other solutions) is an FDA approved hair growth treatment and many balding men and women use it with great success. This particular ingredient is what allows Provillus to advertise their product as FDA approved.

Azelaic acid has been found to clean the skin and potentially inhibit DHT, the hormone responsible for androgenic alopecia.

Combining these two “forces” therefore in theory, may be a more powerful treatment than minoxidil alone. However, no clinical studies have been performed on azelaic acid as a standalone product therefore, whether or not it can stop hair loss is purely conjecture.

Oral Ingredients:

The Provillus oral solution contains a number of supposed DHT blockers including saw palmetto for hair loss, Vitamin B6 and Zinc, pumpkin or cucurbita maxima, and nettle root. Because evidence exists that these ingredients may be an effective treatment for benign prostatic hypertrophy (BPH), theories have been produced that they might also effectively treat baldness. Though we can appreciate the aspiration for balding men and women to use herbal products as an “all-natural” replacement for Propecia (finasteride), the problem we have is that most of them only contain anecdotal if any evidence at all that they can successfully treat baldness.

Provillus oral solution also contains a number of components that are said to promote healthy hair growth and cleanse the scalp. These include eleuthero, uva-ursi, muria puama, horsetail, para-aminobenzoid acid (PABA), and magnesium. Understand however, that promoting a healthy scalp and hair is not the same as stimulating newhair growth and hair regrowth, nor does it signify an effective hair loss treatment.

Possible Side Effects

The only side effect that we could find listed on the Provillus website is an upset stomach. It is reported that taking it with food often stops this. Be sure to follow the links to the ingredients listed above as many of them also have potentially reported side effects. Consulting with a physician before taking any herbal hair loss medication is advised.

Dosage

Currently there are no standards on dosages of herbal medications in the United States. In addition, no formal clinical studies have been performed on them for treating baldness. Therefore, the suggested daily value listed on the ingredient package is based on something other than government regulation and scientific study.

Costs

A one month supply of Provillus topical and oral supplement for men or for women costs about $50 per month. Discounted prices are available when bought in bulk.

For the cost of Provillus, one can purchase generic finasteride and generic minoxidil which are FDA approved hair loss treatments for safety and efficacy.

Conclusions and Our Opinion

Given that Provillus topical treatment contains FDA approved hair regrowth ingredient minoxidil; we can at least agree that it may have some marginal benefit for men and women suffering from androgenic alopecia. However, due to the lack of compelling evidence in these other conjectured hair loss solutions, it may be more beneficial and cost effective to spend your money on Propecia (finasteride)for men only and Rogaine (minoxidil) that has helped balding men and women worldwide.